Blar i forfatter "Sekkenes, Hege J."

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    • Overexpression of T-bet, GATA-3 and TGF-ß induces IFN-γ, IL-4/13A, and IL-17A expression in Atlantic salmon 

      Slettjord, Tiril Hoffstrøm; Sekkenes, Hege J.; Chi, Heng; Bøgwald, Jarl; Swain, Trilochan; Dalmo, Roy Ambli; Swain, Jaya Kumari (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-20)
      The overexpression of <i>GATA-3, T-bet</i> and <i>TGF-ß</i> may theoretically induce <i>IL-4/A, IFN-γ</i> and <i>IL-17A</i> expression, respectively. Whether this also applies to fish is not yet known. The plasmid vectors encoding reporter gene (RFP)-tagged <i>T-bet, GATA-3</i> and <i>TGF-ß</i> were used as overexpression tools, transfected into cells or injected intramuscularly to monitor the ...